![]() Hydrocodone is available in combination with other medications, for example, hydrocodone and acetaminophen, and hydrocodone and ibuprofen.May be prescribed with naloxone for those at increased risk of opiate overdosage or who have household members, including children, at risk of accidental ingestion or overdosage.However, hydrocodone may be more constipating than oxycodone. Less potential for constipation, nausea, and vomiting than morphine.Hydrocodone (by itself) is only available in abuse-deterrent, branded, extended-release forms, under the brand names: Hysingla ER, Vantrela ER, and Zohydro ER. ![]() Relieves moderate-to-severe acute and chronic pain not controlled by other pain-relieving medicines.It may also be called an opioid analgesic. Hydrocodone belongs to the group of medicines known as narcotic analgesics.When used to treat cough hydrocodone is thought to act on the central cough reflex. Precisely how hydrocodone relieves pain is unknown, but it is thought to release naturally present opioid-like compounds. Like all full agonists, there is no ceiling effect for analgesia but the risk of side effects such as respiratory and CNS depression are more likely at higher dosages. It is a full opioid agonist that is relatively selective for the mu-opioid receptor, although it can act on other receptors at higher dosages. Hydrocodone works on receptors in the brain and spinal cord to relieve pain.Hydrocodone is an analgesic (pain-reliever) that may be given to treat moderate-to-severe pain that is unresponsive to other, less potent, pain-relieving medicines.Medically reviewed by Carmen Pope, BPharm.
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